Is treatment with scopolamine (Scopoderm) compatible with breast feeding? A breast feeding woman is going on a boat trip to Åland and wants profylaxis for seasickness.
No published information on scopolamine transfer into breast milk was found. Scopolamine has a short half-life of 2.9 +/- 1.2 hours (1). However, Scopoderm is a depot patch of scopolamine with a controlled release of scopolamine over 72 hours. The patch should be applied the day before or at least 5-6 hours before the start of the trip. Steady state is reached 6 hours after the patch is applied. After the removal of the patch the concentration in plasma is slowly decreasing due to a depot of scopolamine in the skin where the patch has been applied (2).
No published information on scopolamine transfer into breast milk was found. The depot preparation, Scopoderm, makes the possible exposition time for the child unnecessary long why other treatments for seasickness should be considered.
Senast ändrad 2018-09-20