Kommersiellt obunden läkemedelsinformation riktad till läkare och sjukvårdspersonal

Drugline nr 23383

Publicerat 2006-10-25

Question

Is treatment with scopolamine (Scopoderm) compatible with breast feeding? A breast feeding woman is going on a boat trip to Åland and wants profylaxis for seasickness.

Answer

No published information on scopolamine transfer into breast milk was found. Scopolamine has a short half-life of 2.9 +/- 1.2 hours (1). However, Scopoderm is a depot patch of scopolamine with a controlled release of scopolamine over 72 hours. The patch should be applied the day before or at least 5-6 hours before the start of the trip. Steady state is reached 6 hours after the patch is applied. After the removal of the patch the concentration in plasma is slowly decreasing due to a depot of scopolamine in the skin where the patch has been applied (2).

Conclusion

No published information on scopolamine transfer into breast milk was found. The depot preparation, Scopoderm, makes the possible exposition time for the child unnecessary long why other treatments for seasickness should be considered.

Asplund A
Böttiger Y

References

  1. Drugline no 13209 (year 1997)
  2. Fass 2006

Senast ändrad 2018-09-20