Kommersiellt obunden läkemedelsinformation riktad till läkare och sjukvårdspersonal


Classification: B

Drug products: Cefadroxil 500 TS - 1 A Pharma, Cefadroxil Mylan, Cefadroxil Sandoz, Cefamox löslig, Cefamox®, Cefamox® löslig, Grüncef

ATC code: J01DB05

Substances: cefadroxil, cefadroxil monohydrate


Large controlled studies on differences between men and women regarding efficacy, safety and pharmacokinetics of cefadroxil are lacking.

Additional information

Pharmacokinetics and dosing

No studies with a clinically relevant sex analysis regarding the pharmacokinetics or dosing of cefadroxil have been found.


In a trial with a three-day oral treatment with cefadroxil 1 g daily in elderly patients with bacteriuri (2 men and 11 women on cefadroxil) only two women had negative urine cultures [1]. The clinical significance of this is uncertain.

Resistance patterns for pathogens often differ between populations. A study in Swedish children (494 boys, 512 girls; <2 years old) between the years 1994-2003 found that the resistance to cefadroxil in the entire population by E. coli was very low (<1%) while enterococci showed total resistance [2].

Adverse effects

No studies with a clinically relevant sex analysis regarding adverse effects of cefadroxil have been found.

Reproductive health issues

Regarding teratogenic aspects, please consult Janusmed Drugs and Birth Defects (in Swedish, Janusmed fosterpåverkan).

Updated: 2020-08-28

Date of litterature search: 2016-02-24


  1. Tzias V, Dontas AS, Petrikkos G, Papapetropoulou M, Dracopoulos J, Giamarellou H. Three-day antibiotic therapy in bacteriuria of old age. J Antimicrob Chemother. 1990;26:705-11. PubMed
  2. Swerkersson S, Jodal U, Åhrén C, Hansson S. Urinary tract infection in small outpatient children: the influence of age and gender on resistance to oral antimicrobials. Eur J Pediatr. 2014;173:1075-81. PubMed
  3. Socialstyrelsens statistikdatabas . Stockholm: Socialstyrelsen. 2015 [cited 2016-03-14.] Socialstyrelsens statistikdatabas

Authors: Linnéa Karlsson Lind, Desirée Loikas

Reviewed by: Mia von Euler

Approved by: Karin Schenck-Gustafsson