Drug products: Acura®, Cetimax, Cetirizin ABECE, Cetirizin Actavis, Cetirizin Apofri, Cetirizin Bluefish, Cetirizin Generics, Cetirizin HEXAL, Cetirizin Mylan, Cetirizin Sandoz, Cetirizin STADA®, Cetirizine Teva, Vialerg, Zanlan, Zyrlex®
ATC code: R06AE07
Substances: cetirizine, cetirizine hydrochloride
Controlled studies on differences between men and women regarding efficacy, safety and pharmacokinetics of cetirizine are lacking.
The present evidence concerning differences between men and women is very limited and do not motivate differentiation in dosing or treatment.
No studies with a clinically relevant sex analysis regarding pharmacokinetics and dosing of cetirizine have been found.
No studies with a clinically relevant sex analysis regarding effects of cetirizine have been found.
No studies with a clinically relevant sex analysis regarding adverse effects of cetirizine have been found.
Regarding teratogenic aspects, please consult Janusmed Drugs and Birth Defects (in Swedish, Janusmed fosterpåverkan).
A prospective study of consecutive patients (85 men and boys, 163 women and girls) attending allergy care showed that acute urticaria was more common in women than in men (73 vs 27%) with a predominance of middle-aged women with a history of atopic eczema. The prevalence of acute urticaria was similar in boys and girls. The drugs of choice were cetirizine and levocetirizine in children while adults more often were treated with fexofenadine, cetirizine, levocetirizine, and systemic corticosteroids .
Date of litterature search: 2017-03-23
Reviewed by: Mia von Euler
Approved by: Karin Schenck-Gustafsson