Drug products: Iktorivil, Iktorivil®, Rivotril
ATC code: N03AE01
Controlled studies on differences between men and women in effect, safety, or pharmacokinetics of clonazepam are lacking.
Pharmacokinetics and dosing
Clearance of clonazepam is similar in men and women . No studies with a clinically relevant sex analysis regarding the dosing of clonazepam have been found.
Effectiveness of clonazepam in the treatment of panic disorder has been studied in clinical trials by the pharmaceutical company. Subgroup analysis did not indicate that there were any differences in treatment outcomes based on patient’s race or sex [1, 2].
No studies with a clinically relevant sex analysis regarding adverse effects of clonazepam have been found.
Reproductive health issues
Regarding teratogenic aspects, please consult Janusmed Drugs and Birth Defects (in Swedish, Janusmed fosterpåverkan).
Date of litterature search: 2019-09-24
- Iktorivil (klonazepam). Summary of Product Characteristics. Swedish Medical Products Agency [updated 2018-05-14, cited 2019-09-24].
- Klonopin (clonazepam). DailyMed [www]. US National Library of Medicine. [updated 2018-12-07, cited 2019-09-24]. Länk
- Läkemedelsstatistik. Stockholm: Socialstyrelsen. 2019 [cited 2020-03-10.] länk
Reviewed by: Mia von Euler, Carl-Olav Stiller, Diana Rydberg
Approved by: Karin Schenck-Gustafsson