Drug products: Iktorivil®, Rivotril
ATC code: N03AE01
Controlled studies on differences between men and women in effect, safety, or pharmacokinetics of clonazepam are lacking.
The present evidence concerning differences between men and women is limited and do not motivate differentiation in dosing or treatment.
Controlled studies examining the influence of sex on clonazepam pharmacokinetics have not been conducted . No studies with a clinically relevant sex analysis regarding the dosing of clonazepam have been found.
Effectiveness of clonazepam in the treatment of panic disorder has been studied in clinical trials. Subgroup analysis did not indicate that there were any differences in treatment outcomes as a function of race or sex .
No studies with a clinically relevant sex analysis regarding adverse effects of clonazepam have been found.
Regarding teratogenic aspects, please consult the Drugs and Birth Defects Database (in Swedish, Janusmed fosterpåverkan).
Date of litterature search: 2013-03-11
Reviewed by: Expertrådet för neurologiska sjukdomar, Ellen Vinge, Lars Lööf
Approved by: Mia von Euler