Drug products: FIRMAGON
ATC code: L02BX02
Substances: degarelix, degarelix acetate
As the substance at present is only used by men, analyses on sex or gender differences have not been considered relevant.
Degarelix is a Gonadotropin Releasing Hormone Receptor Antagonist used for treatment of advanced hormone dependent prostate cancer [1-2]. There is one experimental study published where degarelix was used for ovarian stimulation (5 healthy women, 5 infertile women) . After a single dose degaralix, all the infertile patients achieved sufficient LH downregulation and completed ovarian stimulation without any LH surge. After blastocyst transferal, pregnancy occurred in three out of five women .
Date of litterature search: 2018-12-17
Reviewed by: Karin Schenck-Gustafsson
Approved by: Karin Schenck-Gustafsson