Lactic acid – topicalClassification: B
Drug products: Calmuril, Locobase LPL
ATC code: D02AE01, D02AX
Published controlled studies on differences between men and women regarding efficacy, safety and pharmacokinetics of topical lactic acid are lacking.
Pharmacokinetics and dosing
No studies with a clinically relevant sex analysis regarding the pharmacokinetics or dosing of topical lactic acid have been found.
No studies with a clinically relevant sex analysis regarding the effects of topical lactic acid have been found.
No studies with a clinically relevant sex analysis regarding the adverse effects of topical lactic acid have been found.
Reproductive health issues
Regarding teratogenic aspects, please consult Janusmed Drugs and Birth Defects (in Swedish, Janusmed fosterpåverkan).
A retrospective analysis of patients with eczema or psoriasis on standard dermatological treatment (295 men, 291 women) found that significantly more men than women (79; 63%, 47; 37%) were administered whole-body UV treatment. Also, the results indicated that men had more treatments appointments per individual than women. Women were prescribed more emollients than men .
Date of litterature search: 2022-06-29
- Nyberg F, Osika I, Evengård B. "The Laundry Bag Project"--unequal distribution of dermatological healthcare resources for male and female psoriatic patients in Sweden. Int J Dermatol. 2008;47:144-9. PubMed
- Statistikdatabas för läkemedel. Stockholm: Socialstyrelsen. 2021 [cited 2022-03-15.] länk
- Conise (INSIKT). Kalmar: eHälsomyndigheten. 2021 [cited 2022-06-29.] länk
Reviewed by: Diana Rydberg
Approved by: Karin Schenck-Gustafsson