Tacrolimus
Classification: BATC code: D11AH01
Summary
Controlled studies on differences between men and women regarding efficacy, safety and pharmacokinetics of tacrolimus are lacking.
The present evidence concerning differences between men and women is very limited and do not motivate differentiation in dosing or treatment.
Additional information
Pharmacokinetics and dosing
No difference between men and women has been shown for transdermal absorption in general [1].
Effects
No studies with a clinically relevant sex analysis regarding effects of tacrolimus have been found.
Adverse effects
No studies with a clinically relevant sex analysis regarding adverse effects of tacrolimus have been found.
Reproductive health issues
Regarding teratogenic aspects, please consult the Drugs and Birth Defects Database (in Swedish, Janusmed fosterpåverkan).
Updated: 2019-02-26
Date of litterature search: 2017-03-24
Reviewed by: Mia von Euler
Approved by: Karin Schenck-Gustafsson