Urea
Classification: BATC code: D02AE01
Summary
Controlled studies on differences between men and women on efficacy, safety, and pharmacokinetics for carbamide are lacking.
Additional information
The main indication of carbamide preparations is moisturizing treatment of dry skin [2].
Pharmacokinetics and dosing
No studies with a clinically relevant sex analysis regarding the pharmacokinetics or dosing of carbamide have been found.
Effects
No studies with a clinically relevant sex analysis regarding the effect of carbamide have been found.
Adverse effects
No studies with a clinically relevant sex analysis regarding adverse effects of carbamide have been found.
Reproductive health issues
Regarding teratogenic aspects, please consult Janusmed Drugs and Birth Defects (in Swedish, Janusmed fosterpåverkan).
Other information
A retrospective analysis of patients with eczema or psoriasis on standard dermatological treatment (295 men, 291 women) found that significantly more men than women (79; 63%, 47; 37%) were administered whole-body UV treatment. Also, the results indicated that men had more treatments appointments per individual than women. Women were prescribed more emollients than men [1].
Updated: 2020-10-06
Date of litterature search: 2020-04-17
References
- Nyberg F, Osika I, Evengård B. "The Laundry Bag Project"--unequal distribution of dermatological healthcare resources for male and female psoriatic patients in Sweden. Int J Dermatol. 2008;47:144-9. PubMed
- Canoderm (carbamide). Summary of Product Characteristics. Swedish Medical Products Agency [updated 2019-10-16, cited 2020-04-17]
- Statistikdatabas för läkemedel. Stockholm: Socialstyrelsen. 2019 [cited 2020-03-10.] länk
Reviewed by: Diana Rydberg, Carl-Olav Stiller
Approved by: Karin Schenck-Gustafsson