Mometasone
Information
Hazard 6 P 3 B 0 T 3 Risk Low
The T-value in the score for hazard refers to acute/chronic toxicity. Underlying data for P, B, T and risk comes from Fass.se.
Fass environmental information
Below is Hazard and Risk from Fass environmental information for Asmanex Twisthaler (mometasone) (downloaded 2018-07-04).
Hazard
Persistence: "DT50 (total system) = 81 to 105 days (OECD 308)." Mometasone is slowly degraded in the environment.
Bioaccumulation: Log Kow: pH 5 = 4.66, pH 7 = 4.68, pH 9 = 4.81. "BCFwhole body, total residues = 104.9 to 107.1. Since BCF < 500, mometasone furoate has low potential for bioaccumulation."
Chronic toxicity: There is NOEC for 3 trophic levels, lowest fish (Pimephales promelas) (OECD 210) NOEC 32d (total length and dry weight) = 0.14 microg/L.
Risk
PEC/PNEC is based on sales data in Sweden in year 2015. PEC/PNEC = 0.42 which gives the risk low.
References
Author: Health and Medical Care Administration, Region Stockholm