The data on hazard and risk are based on previous environmental information on Fass.se.
Environmental information is missing on fass.se (2018-10-30). It is voluntary for manufacturers to provide information about environmental impact on fass.se.
Underlying data for P, B, T and risk are from Fass.
Fass environmental information for Alvesco (ciklesonide) (downloaded 2013-11-14).
Persistence: "Ciclesonide is not readily biodegradable according to the results of a Closed-Bottle-Test."
Bioaccumulation: Log Pow = 3.93.
Toxicity: See under the heading Risk.
"It is not possible to calculate the PNEC from our data. Data from short-term tests (Algae, daphnia, zebrafish) are available for ciclesonide. In order to calculate the PNEC from short-term test, an EC or LC50-value is needed. Because of the low solubility of ciclesonide, only a very low saturation concentration was reached in the tests, which was not effective. So there is no effective concentration, which could be used for the determination of the PNEC."
Author: Health and Medical Care Administration, Region Stockholm