Cyproterone

Information

The T-value in the score for hazard refers to acute toxicity. Underlying data for P, B, T and risk are from Fass.

Below is Hazard and Risk from Fass environmental information for Androcur (cyproterone) (downloaded 2018-11-01).

Hazard

Persistence: "CO2 evolution test, guideline OECD 301B (80).Test results 0% degradation in 28 days."

Bioaccumulation OECD 117: Log P_ow = 3.36.

Acute toxicity OECD 202: There are data for 1 trophic level for crustaceans (Daphnia magna) 2.4 mg/L.

Risk

Risk of environmental impact of cyproterone acetate cannot be excluded, since there is not sufficient ecotoxicity data available.

Article Predicted critical environmental concentrations for 500 pharmaceuticals

Critical effect concentration (CEC) for cyproterone is 1 786 ng/L. Log P is set to 3.6.