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Docetaxel

Hazard - P - B 0 T - Risk Cannot be excluded

Information

Underlying data for B comes from the assessment report. Information about P, ​​T and risk comes from Fass.

Assessment report

Assessment report for Docetaxel Winthrop, Doc. Ref No.: EMA/449127/2010, 20.05.2010

Hazard

Persistence: No data.

Bioaccumulation: "The log Kow of the active ingredient is 3.2 (calculated)."

Toxicity: "The MAH (Marketing authorization holder, red. kommentar) has further provided information on fate (sorption, hydrolysis, aerobic biodegradation) and effects (acute toxicity test on Daphnia, minimal inhibiting concentration for micro-organisms) of docetaxel in the environment without submitting any study report." No data is available in the report.

Other information

"The MAH has predicted an environmental concentration in surface water of 3.9 10-4 μg/l and concluded that no further environmental risk assessment is necessary."

Below is Hazard and Risk from Fass environmental information for Doxetaxel Actavis (downloaded 2018-11-01).

Hazard

Persistence: No data.

Bioaccumulation: No data.

Toxicity: No data.

Risk

Risk of environmental impact of docetaxel cannot be excluded, since no ecotoxicity data are available.

Author: Health and Medical Care Administration, Region Stockholm