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Isosorbide mononitrate

Hazard 4* P 3* B 0 T 1* Risk Cannot be excluded

Information

The T-value in the score for hazard refers to acute toxicity. Underlying data for P, B, T and risk are from Fass.se.

Fass environmental information

Fass environmental information for Imdur (isosorbide mononitrate) (downloaded 2018-07-06).

Hazard

Persistence: No data.

Bioaccumulation: Log P = 1.15. Metod QSAR – Log Kow: Log P = - 0.15.

Acute toxicity: There is data for 1 trophic level for crustaceans (Daphnia magna) EC50 > 120 mg/L.

Risk

Sales in Sweden are available for 2014. "Since no long term effect data are available, and only short term data from one species, the water flea, is available, it is not possible to calculate the PNEC (Ref 1). Therefore, the statement "Risk of environmental impact of isosorbide mononitrate cannot be excluded, since there is not sufficient ecotoxicity data available" is used."

Author: Department of Strategic Careers, Stockholm County Council.