The T-value in the hazard score refers to chronic toxicity.
Assessment report for Latuda (lurasidone), 23 January 2014, EMA/113836/2014.
Persistence: "DT50 or ready biodegradability = 191 days"
Bioaccumulation: BCF = 2 798–2 585.
Chronic toxicity: There is NOEC for three trophic levels, lowest NOEC for crustacean (Daphnia magna) 26 microg/L.
The risk, PEC/PNEC, calculated from data in the assessment report from a European perspective:
PEC = 0.8 microg/L
PNEC = Lowest NOEC 26 microg/L/10 (Assessment Factor (AF) for three chronic studies) = 2.6 microg/L
PEC/PNEC = 0.308 which gives the risk low.
"In conclusion, lurasidone is not a PBT substance and is not expected to pose a risk to the environment."
Author: Department of Strategic Careers, Stockholm County Council.