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Mitoxantrone

Hazard - P - B 0 T - Risk Cannot be excluded

Information

Underlying data for B is from Fass.

Fass environmental information

Fass environmental information for Novantrone (mitoxantrone) (downloaded 2019-04-25).

Hazard

Persistence: No data.

Bioaccumulation: "An estimated log Pow of 2,28 (unknown method) ... indicates that mitoxantrone has a low potential to bioaccumulate. Log Pow < 4 which justifies use of the phrase “Mitoxantron has low potential for bioaccumulation”."

Toxicity: No data.

Risk

"According to the European Medicines Agency guideline on environmental risk assessment of medicinal products (EMA/CHMP/SWP/4447/00), use of mitoxantron is unlikely to represent a risk for the environment, because the predicted environmental concentration (PEC) is below the action limit 0,01 μg/L."

Risk of environmental impact of mitoxantrone cannot be excluded, since no ecotoxicity data are available.

It is voluntary for manufacturers to provide information about environmental impact on fass.se.

Author: The Pharmaceutical unit of Region Stockholm