Drug products: Microlax®
ATC code: A06AG11
Substances: sodium lauryl sulfoacetate
Published controlled studies on differences between men and women in sodium lauryl sulphate efficacy and safety are lacking
No studies with a clinically relevant sex analysis regarding the pharmacokinetics or dosing of sodium lauryl sulphate have been found.
No studies with a clinically relevant sex analysis regarding the effects of sodium lauryl sulphate have been found.
The skin irritability of volunteers to sodium lauryl sulphate (2% aqueous) has been studied by measuring skin vapour loss (SVL) (23 men, 15 women). The study found that female skin is more easily irritated .
Regarding teratogenic aspects, please consult Janusmed Drugs and Birth Defects (in Swedish, Janusmed fosterpåverkan).
Date of litterature search: 2015-08-20
Reviewed by: Mia von Euler
Approved by: Karin Schenck-Gustafsson