Drug products: Microlax®
ATC code: A06AG11
Substances: sodium lauryl sulfoacetate
Controlled studies on differences between men and women in sodium lauryl sulphate efficacy and safety are lacking
The present evidence concerning differences between men and women is limited and do not motivate differentiation in dosing or treatment.
No studies with a clinically relevant sex analysis regarding the pharmacokinetics or dosing of sodium lauryl sulphate have been found.
No studies with a clinically relevant sex analysis regarding the effects of sodium lauryl sulphate have been found.
The skin irritability of volunteers to sodium lauryl sulphate (2% aqueous) has been studied by measuring skin vapour loss (SVL) (23 men, 15 women). The study found that female skin is more easily irritated .
Regarding teratogenic aspects, please consult Janusmed Drugs and Birth Defects (in Swedish, Janusmed fosterpåverkan).
Date of litterature search: 2015-08-20
Reviewed by: Mia von Euler
Approved by: Karin Schenck-Gustafsson