Dexrazoxane
Summary
Persistence. It cannot be excluded that dexrazoxane is persistent, as data are lacking.
Bioaccumulation. Dexrazoxane has low potential for bioaccumulation.
Toxicity. It cannot be excluded that dexrazoxane is toxic, as data are lacking.
Risk. Risk of environmental impact of dexrazoxane cannot be excluded, since no ecotoxicity data are available.
This summary information comes from fass.se.
Detailed information
European Medicines Agency’s scientific discussion for Savene
According to the European Medicines Agency’s scientific discussion for Savene (dexrazoxane) from 2006: "Ecotoxicity/environmental risk assessment The drug product has been designated as an Orphan Drug in the European Union, and due to the Guideline (CHMP/SWP/4447/00) no environmental risk assessment has been performed."
Fass environmental information
Fass environmental information for Savene from CampusPharma (retrieved on 2025-06-18).
Hazard
Persistence: No data.
Bioaccumulation: Log Kow = 0.025.
Toxicity: No data.
Risk
Risk of environmental impact of dexrazoxane cannot be excluded, since no ecotoxicity data are available.
Author: Health and Medical Care Administration, Region Stockholm