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Dexrazoxane

Summary

Persistence. It cannot be excluded that dexrazoxane is persistent, as data are lacking.

Bioaccumulation. Dexrazoxane has low potential for bioaccumulation.

Toxicity. It cannot be excluded that dexrazoxane is toxic, as data are lacking.

Risk. Risk of environmental impact of dexrazoxane cannot be excluded, since no ecotoxicity data are available.

 

This summary information comes from fass.se.

Detailed information

European Medicines Agency’s scientific discussion for Savene

According to the European Medicines Agency’s scientific discussion for Savene (dexrazoxane) from 2006: "Ecotoxicity/environmental risk assessment The drug product has been designated as an Orphan Drug in the European Union, and due to the Guideline (CHMP/SWP/4447/00) no environmental risk assessment has been performed."

Fass environmental information

Fass environmental information for Savene from CampusPharma (retrieved on 2025-06-18).

Hazard

Persistence: No data.

Bioaccumulation: Log Kow = 0.025.

Toxicity: No data.

Risk

Risk of environmental impact of dexrazoxane cannot be excluded, since no ecotoxicity data are available.

Author: Health and Medical Care Administration, Region Stockholm