Mupirocin
Summary
Persistence. It cannot be excluded that mupirocin is persistent, due to lack of data.
Bioaccumulation. Mupirocin has low potential for bioaccumulation.
Toxicity. Mupirocin has low acute toxicity. See, however, the comment under the heading "Detailed information".
Risk. Risk of environmental impact of mupirocin cannot be excluded since there is not sufficient ecotoxicity data available.
This summary information comes from fass.se.
Detailed information
Fass environmental information
Fass environmental information for Bactroban (mupirocin) from GlaxoSmithKline AB (retrieved on 2025-11-26).
Hazard
Persistence: No data.
Bioaccumulation: Several Log Dow values at different pH according to TAD 3.02 and QSAR. At pH 7: 2.28 (TAD 3.02) and 0.30 (QSAR).
Acute toxicity: There is data for 1 trophic level, crustacea (Daphnia magna) EC50 > 1000000 microg/L (TAD 3.11/OECD 202). Comment: Values reported as greater than are not according to the guidelines. The actual value may be lower.
Risk
PEC/PNEC is based on sales data in Sweden in year 2022.
PEC = 0.000114 microg/L.
"PNEC cannot be calculated because data is not available for all three (algae, crustacean and fish) of the toxicity endpoints."
Risk of environmental impact of mupirocin cannot be excluded since there is not sufficient ecotoxicity data available.
References
Author: Health and Medical Care Administration, Region Stockholm