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Acetylsalicylic acid

Information

This summary information comes from Fass (Bayer).

Persistence. Acetylsalicylic acid is degraded in the environment.
Bioaccumulation. Acetylsalicylic acid has low potential for bioaccumulation.
Toxicity. Acetylsalicylic acid has moderate chronic toxicity.
Risk. The use of acetylsalicylic acid (sales data Sweden 2018) has been considered to result in low environmental risk.

Detailed information

Fass environmental information for Aspirin (acetylsalicylic acid) from Bayer (downloaded 2021-06-24)

Hazard

Persistence according to OECD 301F: "The substance was introduced into the test system at a concentration of 200 mg/L as theoretical oxygen demand (ThOD) and was found to be degraded to 69.6% after 10 and 83.3 % after 28 days. Hence, acetylsalicylic acid can be regarded as readily biodegradable."

Bioaccumulation: "The log Kow/20 °C was - 0.32, - 1.62, and - 1.61 at pH 5, 7 and 9, respectively."

Chronic toxicity: There is NOEC for 3 trophic levels, lowest NOEC for fish 283 microg/L.

Risk

PEC/PNEC is based on sales data in Sweden in year 2018. PEC/PNEC = 0,7 which gives the risk low.

Fass environmental information for Trombyl (acetylsalicylic acid) from Pfizer (downloaded 2021-06-24)

Hazard

Persistence: It cannot be excluded that acetylsalicylic acid is persistent, due to the lack of data.

Bioaccumulation: It cannot be excluded that acetylsalicylic acid bioaccumulates, due to the lack of data.

Toxicity: It cannot be excluded that acetylsalicylic acid is toxic, due to the lack of data.

Risk

Risk: Risk of environmental impact cannot be excluded, due to the lack of environmental toxicity data.

Report Pharmaceutial residues in the Stockholm aquatic environment

Acetylsalicylic acid and penicillins were eliminated despite their very high consumption and discharge to sewage because they break down very quickly, both in the treatment of wastewater and in natural waters.

Author: Health and Medical Care Administration, Region Stockholm