Underlying information about P, B, T and risk comes from Fass. Amitriptyline's major metabolite is nortriptyline. See also nortriptyline.
Fass environmental information for Amitriptylin Abcur (downloaded 2018-11-06).
Persistence: No data.
Bioaccumulation: Log Kow = 4.92 (unknown method).
Toxicity: No data.
Risk of environmental impact of amitriptyline cannot be excluded, since no ecotoxicity data are available.
Amitriptyline has been found in treated wastewater (up to 24 ng/L), surface water (up to 9.1 ng/L) and sludge (up to 170 microg/kg dry weight) at national measurements. The IVL report also presents results from regional screening programs. Amitriptyline has been found in treated wastewater (over 20 ng/L) in Stockholm County during the last five-year period (2012-2016).
Author: The Pharmaceutical unit of Region Stockholm