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Persistence. Atomoxetine is potentially persistent.

Bioaccumulation. Atomoxetine has low potential for bioaccumulation.

Toxicity. Atomoxetine has high chronic toxicity.

Risk. The use of atomoxetine (sales data Sweden 2020) has been considered to result in insignificant environmental risk.


This summary information comes from Fass.se.

Detailed information

Fass environmental information

Fass environmental information for Strattera (atomoxetine) from Lilly (downloaded 2024-04-26).


Persistence: "The environmental fate data from the water-sediment degradation study (OECD 308) was used to determine the persistence classification of atomoxetine. Since the calculated DT50 values for two different systems were greater than 120 days, atomoxetine is considered to be potentially persistent."

Bioaccumulation: The log Kow of atomoxetine at pH 4, 7, and 9 was determined to be 0,104; 0,676; and 2,81; respectively.

Chronic toxicity: There are data for 3 trophic levels, most sensitive fish (Fathead minnow) NOEC 32 microg/L.


PEC/PNEC is based on sales data in Sweden in year 2020. PEC/PNEC = 0.004 which gives the risk insignificant.

Author: Health and Medical Care Administration, Region Stockholm