Hazard 9* P 3* B 3 T 3* Risk Cannot be excluded
The T-value in the score for hazard refers to chronic toxicity. Underlying data for P, B and T comes from Fass.se, see below.
Fass environmental information
Fass environmental information for atovaquone, Malarone (atovaquone, proguanil) (downloaded 2018-06-26).
Persistence: It can not be ruled out that atovaquone is persistence because data is missing.
Bioaccumulation: Log Kow = 5.31 at pH 7.
Chronic toxicity: There is NOEC for 8 days for 1 trophic level: crustacean 0.083 microg/L.
"The appropriate degradation data are not available to assign PBT/vPvB criteria."
"Risk of environmental impact of atovaquone cannot be excluded, since there is not sufficient ecotoxicity data available."
Author: Health and Medical Care Administration, Region Stockholm