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Hazard 9* P 3* B 3 T 3* Risk Cannot be excluded


The T-value in the score for hazard refers to chronic toxicity. Underlying data for P, B and T comes from Fass.se, see below.

Fass environmental information

Fass environmental information for atovaquone, Malarone (atovaquone, proguanil) (downloaded 2018-06-26).


Persistence: It can not be ruled out that atovaquone is persistence because data is missing.

Bioaccumulation: Log Kow = 5.31 at pH 7.

Chronic toxicity: There is NOEC for 8 days for 1 trophic level: crustacean 0.083 microg/L.

PBT/vPvB assessment

"The appropriate degradation data are not available to assign PBT/vPvB criteria."


"Risk of environmental impact of atovaquone cannot be excluded, since there is not sufficient ecotoxicity data available."

Author: Health and Medical Care Administration, Region Stockholm