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Beclomethasone dipropionate

Hazard 6* P 3 B 0 T 3* Risk Cannot be excluded

Information

The T-value in the score for hazard refers to acute toxicity.

The data on hazard and risk are based on previous environmental information on fass.se. Teva has for AeroBec (beclomethasone dipropionate) written that there are no data in the environmental information (retrieved 2019-12-13). It is voluntary for manufacturers to provide information about environmental impact on fass.se.

Fass environmental information

Fass environmental information for Becotide Nasal (beclomethasone dipropionate) from GlaxoSmithKline (downloaded 2013-09-04).

Hazard

Persistence: "Ready Biodegradation = 3% in 28d (TAD 3.11, Jenkins 1995). This substance is not readily biodegradable."

Bioaccumulation: Log Pow = 3.49.

Toxicity: There is data for one trophic level crustacean (Daphnia magna) "EC50 48 h > 3,74 microg/L (highest concentration testedsolubility limit) microg/L."
Comment. Values reported as greater than are not according to the guidelines. The actual value may be lower.

Risk

Risk of environmental impact of beclomethasone dipropionate cannot be excluded, since there is not sufficient ecotoxicity data available.

Pharmaceuticals residues in the aquatic environment in Region Stockholm

Beclomethasone dipropionate has been found in purified wastewater in Region Stockholm 2018.
Concentrations up to 33 ng/L have been measured.

Author: Health and Medical Care Administration, Region Stockholm