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Hazard 6 P 3 B 0 T 3 Risk Insignificant


The T-value in the score for hazard refers to chronic toxicity. Underlying data for P, B and T comes from Fass.

Fass environmental information

Fass environmental information for Jevtana (cabazitaxel) (downloaded 2018-06-26).


Persistence: Test showed 17.76 % degradation in 28 days (guideline OECD 301B).

Bioaccumulation: Log Pow = 3.78 at pH 7 (guideline OECD 107).

Chronic toxicity: There is NOEC for 3 trophic levels, lowest NOEC 21 days for crustacean (Daphnia magna) 8.9 microg/L.


PEC/PNEC is based on sales data in Sweden in year 2015. PEC/PNEC = 0.00000843, which gives the risk insignificant.

Author: Health and Medical Care Administration, Region Stockholm