Persistence. Calcipotriol is potentially persistent.
Bioaccumulation. Calcipotriol has high potential for bioaccumulation.
Toxicity. It cannot be excluded that calcipotriol is toxic, due to the lack of data.
Risk. Risk of environmental impact of calcipotriol cannot be excluded, due to the lack of environmental toxicity.
The data on hazard and risk are based on previous environmental information on fass.se. Environmental information is missing (2022-08-17). It is voluntary for manufacturers to provide information about environmental impact on fass.se.
Fass environmental information for Daivobet (betamethasone, calcipotriol) (downloaded 2018-11-07).
Persistence: "Calcipotriol is not readily biodegradable. It has been tested according to the test guideline OECD 301F and a biodegradation of -2 ± 2% was found after 28 days."
Bioaccumulation: Log Pow, calcipotriol = 4.9.
Toxicity: No data.
"Because of the lack of data it is not possible to calculate a valid PNEC and a risk of environmental impact cannot be excluded."
Author: Health and Medical Care Administration, Region Stockholm