Underlying information for P, B, T and risk are from Fass.
Fass environmental information for Cefotaxim Villerton (downloaded 2018-10-31).
Persistence: No data.
Bioaccumulation: "Log P= -1.4 at neutral pH (predicted by ChemAxon)."
Toxicity: No data.
Risk of environmental impact of cefotaxime cannot be excluded, since no ecotoxicity data is available.
Critical effect concentration (CEC) for cefotaxime is 1 300 000 ng/L. Log P is set to 0.6.
Studies have shown that even low concentrations of antibiotics in the environment can contribute to antibiotic resistance and therefore as little as possible should end up in our environment.
For antibiotics in general, it is recommended that these drugs are used as restrictively as possible without risking the patient's health.
Author: Health and Medical Care Administration, Region Stockholm