Gå till innehåll

Kommersiellt obunden läkemedelsinformation riktad till läkare och sjukvårdspersonal



The data on hazard and risk are based on previous environmental information on fass.se. Environmental information is missing (2022-01-17). It is voluntary for manufacturers to provide information about environmental impact on fass.se.


Persistence. Ciclesonide is slowly degraded in the environment.
Bioaccumulation. Ciclesonide has low potential for bioaccumulation.
Toxicity. It cannot be excluded that ciclesonide is toxic, due to the lack of data.
Risk. Risk of environmental impact cannot be excluded, since there is not sufficient ecotoxicity data available. 

Fass environmental information

Fass environmental information for Alvesco (ciclesonide) from Takeda Pharma (downloaded 2013-11-14).


Persistence: "Ciclesonide is not readily biodegradable according to the results of a Closed-Bottle-Test."

Bioaccumulation: Log Pow = 3.93.

Acut toxicity: See under the heading Risk.


"It is not possible to calculate the PNEC from our data. Data from short-term tests (Algae, daphnia, zebrafish) are available for ciclesonide. In order to calculate the PNEC from short-term test, an EC or LC50-value is needed. Because of the low solubility of ciclesonide, only a very low saturation concentration was reached in the tests, which was not effective. So there is no effective concentration, which could be used for the determination of the PNEC."

Author: Health and Medical Care Administration, Region Stockholm