Cyproterone
Summary
Persistence. It cannot be excluded that cyproterone is persistent, due to the lack of data.
Bioaccumulation. Cyproterone has low potential for bioaccumulation.
Toxicity. Cyproterone has very high acute toxicity.
Risk. Risk of environmental impact of cyproterone cannot be excluded, since there is not sufficient ecotoxicity data available.
This summary information about cyproterone comes from Zyrona (cyproterone, ethinyl estradiol) from the pharmaceutical company Orifarm Generics AB. The following is written: "The environmental information for cyproterone comes from the company Bayer for Diane (cyproterone, ethinyl estradiol)." According to the Swedish Medical Products Agency's website, Diane was removed from the Swedish market on 2020-12-18.
Detailed information
Fass environmental information
Fass environmental information about cyproterone comes from Zyrona (cyproterone, ethinyl estradiol) from the pharmaceutical company Orifarm Generics AB (downloaded 2024-12-10). The following is written: "The environmental information for cyproterone comes from the company Bayer for Diane (cyproterone, ethinyl estradiol)." According to the Swedish Medical Products Agency's website, Diane was removed from the Swedish market on 2020-12-18.
Hazard
Persistence: No data.
Bioaccumulation OECD 117: Log Dow = 3.36. "As the log Dow was < 4 cyproterone acetate is not considered bioaccumulative which qualifies for the phrase “Cyproterone acetate has low potential for bioaccumulation.”
Acute toxicity OECD 202: There are data about EC50 for 1 trophic level for crustaceans (Daphnia magna) 2.4 mg/L.
Risk
Risk of environmental impact of cyproterone acetate cannot be excluded, since there is not sufficient ecotoxicity data available.
References
Author: Health and Medical Care Administration, Region Stockholm