Hazard 5 P 3 B 0 T 2 Risk Low
The T-value in the score for hazard refers to acute toxicity. Underlying data for P, B, T and risk are from Fass.
Fass environmental information
Fass environmental information for Dipyramidol Alternova developed by the company Boehringer Ingelheim for Asasantin Retard, Persantin Depot (downloaded 2016-08-22).
Persistence: "In a 28d ready biodegradability study in accordance with OECD test Guideline 301F (GLP) 3% biodegradation of Dipyridamol was observed. [---] In an OECD Guideline 121 (GLP) study the Log Koc for Dipyradimol was determined to 3.91, indicating potential for distribution to soil/sludge, though not classified as strong (> 4). [---] Dipyridamol did not pass the ready degradation test (OECD 301F) and data on abiotic degradation is lacking. [---] Based on these data combined Dipyridamol is considered "potentially persistent"."
Bioaccumulation: "n-octanol/water partition coefficient of < 4 at pH 7 and a calculated BCF of 5.7, dipyridamol is considered to have "low potential for bioaccumulation"."
Acute toxicity: There is data for 3 trophic levels, lowest for algae (Scenedesmus subspicatus) 2.36 mg/L.
PEC/PNEC is based on sales data in Sweden in year 2013. PEC / PNEC = 0.21 which gives the risk low.
No new environmental information for dipyramidole is published on Fass.se (2018-08-20).
Pharmaceutical analyses of water in Stockholm County
Dipyridamol has not been found in purified wastewater, surface water or in drinking water in Stockholm County during the last five-year period (2012-2016).
Author: Health and Medical Care Administration, Region Stockholm