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Fosamprenavir

Hazard 3 P 3 B 0 T 0 Risk Insignificant

Information

The T-value in the score for hazard refers to chronic toxicity.

Fass environmental information

Fass environmental information for Telzir (fosamprenavir) (downloaded 2018-06-15).

Hazard

Persistence: "Fosamprenavir is not readily biodegradable nor inherently biodegradable."

Bioaccumulation: "Log P < 1.00 (method unknown)."

Toxicity: There are data for 3 trophic levels, most sensitive crustacean (Ceriodaphnia dubia) NOEC = 100 mg/L.

Risk

PEC/PNEC is based on sales data in Sweden in year 2014. PEC/PNEC = 1.80 x 10-7, i.e. insignificant.

Telzir: EPAR - Scientific Discussion 2005-12-05

"An assessment of the risk was performed and no significant risk to the environment related to the use of fosamprenavir is anticipated."

Author: Health and Medical Care Administration, Region Stockholm