Fosamprenavir
Hazard
3
P
3
B
0
T
0
Risk
Insignificant
Information
The T-value in the score for hazard refers to chronic toxicity.
Fass environmental information
Fass environmental information for Telzir (fosamprenavir) (downloaded 2018-06-15).
Hazard
Persistence: "Fosamprenavir is not readily biodegradable nor inherently biodegradable."
Bioaccumulation: "Log P < 1.00 (method unknown)."
Toxicity: There are data for 3 trophic levels, most sensitive crustacean (Ceriodaphnia dubia) NOEC = 100 mg/L.
Risk
PEC/PNEC is based on sales data in Sweden in year 2014. PEC/PNEC = 1.80 x 10-7, i.e. insignificant.
Telzir: EPAR - Scientific Discussion 2005-12-05
"An assessment of the risk was performed and no significant risk to the environment related to the use of fosamprenavir is anticipated."
Author: Health and Medical Care Administration, Region Stockholm