Fosamprenavir
Summary
Persistence. Fosamprenavir is potentially persistent.
Bioaccumulation. Fosamprenavir has low potential for bioaccumulation.
Toxicity. Fosamprenavir has low chronic toxicity.
Risk. The use of fosamprenavir (sales data Sweden 2014) has been considered to result in insignificant environmental risk.
This summary information is based on previously published environmental data for Telzir (fosamprenavir) from GlaxoSmithKline (retrieved on 2018-06-15) on fass.se. As of July 1, 2025, no environmental information is available on fass.se for fosamprenavir.
Detailed information
Fass environmental information
Fass environmental information for Telzir (fosamprenavir) from GlaxoSmithKline (retrieved on 2018-06-15).
Hazard
Persistence: "Fosamprenavir is not readily biodegradable nor inherently biodegradable."
Bioaccumulation: "Log P < 1.00 (method unknown)."
Toxicity: There are data for 3 trophic levels, most sensitive crustacean (Ceriodaphnia dubia) NOEC = 100 mg/L.
Risk
PEC/PNEC is based on sales data in Sweden in year 2014. PEC/PNEC = 1.80 x 10-7, i.e. insignificant.
Telzir: EPAR - Scientific Discussion 2005-12-05
"An assessment of the risk was performed and no significant risk to the environment related to the use of fosamprenavir is anticipated."
Author: Health and Medical Care Administration, Region Stockholm