Isoniazid
Summary
Persistence. It cannot be excluded that isoniazid is persistent, as data are lacking.
Bioaccumulation. Isoniazid has low potential for bioaccumulation.
Toxicity. Isoniazid has very high acute toxicity.
Risk. Risk of environmental impact of isoniazid cannot be excluded, since there is not sufficient ecotoxicity data available.
This summary information comes from fass.se.
Detailed information
Fass environmental information
Fass environmental information for Nydrazid (isoniazid) from Meda (retrieved on 2025-07-09). Nydrazid has been deregistered, but Sandoz AS refers, for example in the case of Rimactazid (isoniazid, rifampicin), to Meda’s environmental information for isoniazid.
Hazard
Persistence: No data.
Bioaccumulation: "An experimentally derived Log Kow of -0,70 (unknown method) ... indicates that isoniazid has low potential for bioaccumulation".
Acute toxicity: Data are available for one trophic level: crustaceans (Daphnia magna). EC₅₀ (24 hours, immobilisation) = 406 µg/L (OECD 202).
Risk
Risk of environmental impact of isoniazid cannot be excluded, since there is not sufficient ecotoxicity data available.
References
Author: Health and Medical Care Administration, Region Stockholm