The T-value in the score for hazard refers to acute/chronic toxicity. Underlying data for P, B and T comes from Fass, see below.
Fass environmental information for Lomir SRO (isradipine), (downloaded 2018-06-27).
Persistence: "7-12 % degradation in 28 days, not readily biodegradable (OECD 301B). The phrase “Isradipine is potentially persistent” is thus chosen."
Bioaccumulation: Log Kow = 4.1 (OECD 107).
Acute toxicity: There is data for 3 trophic levels, lowest for fish (Oncorhynchus mykiss, rainbow trout) LC50 96 h (mortality) 76 microg/L.
PEC/PNEC is based on sales data in Sweden in year 2015. PEC/PNEC = 0.0081 which gives the risk insignificant.
"Based on the available information, isradipine fulfills the screening criteria for a potential PBT substance. No definitive judgement on PBT can be made as only data for PBT screening are available, not for definitive PBT assessment."
Author: Health and Medical Care Administration, Region Stockholm