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The data on hazard and risk on levocabastine are based on previous environmental information on fass.se (2011-11-23). Environmental information is missing on fass.se (2021-10-15). It is voluntary for manufacturers to provide information about environmental impact on fass.se.


Persistence. Levocabastine is potentially persistent.
Bioaccumulation. Levocabastine has no significant bioaccumulation potential.
Toxicity. Levocabastine has moderate acute toxicity.
Risk. The use of levocabastine (sales data Sweden 2010) has been considered to result in insignificant environmental risk.

Detailed information

Fass environmental information

Fass environmental information for Livostin (levocabastine) from McNeil (downloaded 2011-11-23).


Persistence: "Not readily biodegradable in a CO2-evolution test according to FDA-guideline 3.11. The substance is potentially persistent."

Bioaccumulation: "Log Kow = 1.75. The partition coefficient is determined between n-octanol and an aqueous buffer solution at pH =8.0. A single extraction method was used. As log Kow < 3, levocabastine has no significant bioaccumulation potential."

Toxicity: There are data for 3 trophic levels, most sensitive algae (Selenastrum capricornutum) EC50 10 mg/L.


PEC/PNEC is based on sales data in Sweden in year 2010. PEC/PNEC = 0.000021 which gives the risk insignificant.

Author: Health and Medical Care Administration, Region Stockholm