Hazard 6* P 3 B 0 T 3* Risk Cannot be excluded
The T-value in the score for hazard refers to acute toxicity. Underlying data for P, B, T and risk are from Fass.
Fass environmental information for Nozinan (levomepromazine) (downloaded 2018-11-01).
Persistence: "Test showed 13% degradation in 28 days (ISO 9439). [---] Levomepromazine fails to pass the criteria for ready biodegradability which justifies the phrase “levomepromazine is potentially persistent”."
Bioaccumulation OECD 107: log Kow at pH 7 = 0.38.
Acute toxicity: Data available for 1 trophic level for crustaceans (Daphnia magna) 700 microg/L.
"Risk of environmental impact of Levomepromazine cannot be excluded, since there is not sufficient data to calculate a PEC/PNEC ratio."
Levomepromazine has been included in screening programs both regionally within the Stockholm area and nationally but has been below the LOQ (quantitative limit value).
Author: Health and Medical Care Administration, Region Stockholm