Underlying data for P and B comes from earlier Fass environmental information. The T value comes from the brochure Environmentally classified pharmaceuticals 2014–2015. Environmental information is missing on fass.se (2018-12-05). It is voluntary for manufacturers to provide information about environmental impact on fass.se. Risk comes from the Report Goodpoint 2016.
Fass environmental information for Primodium (loperamide) (downloaded 2013-05-28).
Persistence: No data.
Bioaccumulation: Loperamide has a high potential for bioaccumulation.
Use of loperamide has been assessed to cause insignificant environmental risk.
Loperamide has been detected in treated wastewater and fish in Stockholm County in the last five years (2012–2016). Loperamide has also been included in the measurement program for 2017 but has not been detected.
The levels in fish are not relevant comparing to human plasma levels. Effect studies are missing. Loperamide may be excluded from monitoring programs due to low risk.
Author: Health and Medical Care Administration, Region Stockholm