Persistence. No data.
Bioaccumulation. No data.
Toxicity. No data.
Risk. See the report from Goodpoint.
Environmental information is missing on fass.se for medroxyprogesterone acetate (2020-01-18). It is voluntary for manufacturers to provide information on environmental impact on fass.se.
Based on the ability to bind to the androgen receptor, bind to SHBG (Sex Hormone Binding Globulin) and studies on fish make medroxyprogesterone a much lower environmental risk than levonorgestrel and norethisterone. The ability of a substance to activate the androgen receptor in fish probably contributes to increased risk of environmental impact, and binding to SHBG is believed to contribute to increased bioconcentration (and thus potency) in fish.
Author: Health and Medical Care Administration, Region Stockholm