Underlying data for B is from Fass.
Fass environmental information for Novantrone (mitoxantrone) (downloaded 2019-04-25).
Persistence: No data.
Bioaccumulation: "An estimated log Pow of 2,28 (unknown method) ... indicates that mitoxantrone has a low potential to bioaccumulate. Log Pow < 4 which justifies use of the phrase “Mitoxantron has low potential for bioaccumulation”."
Toxicity: No data.
"According to the European Medicines Agency guideline on environmental risk assessment of medicinal products (EMA/CHMP/SWP/4447/00), use of mitoxantron is unlikely to represent a risk for the environment, because the predicted environmental concentration (PEC) is below the action limit 0,01 μg/L."
Risk of environmental impact of mitoxantrone cannot be excluded, since no ecotoxicity data are available.
It is voluntary for manufacturers to provide information about environmental impact on fass.se.
Author: The Pharmaceutical unit of Region Stockholm