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Mitoxantrone

Summary

Persistence. It cannot be excluded that mitoxantrone is persistent, due to lack of data.

Bioaccumulation. Mitoxantrone has low potential for bioaccumulation.

Toxicity. It cannot be excluded that mitoxantrone is toxic, due to lack of data.

Risk. Risk of environmental impact of mitoxantrone cannot be excluded, since no ecotoxicity data are available.

 

This summary information comes from fass.se.

Detailed information

Fass environmental information

Fass environmental information for Novantrone (mitoxantrone) (downloaded 2019-04-25).

Hazard

Persistence: No data.

Bioaccumulation: "An estimated log Pow of 2,28 (unknown method) ... indicates that mitoxantrone has a low potential to bioaccumulate. Log Pow < 4 which justifies use of the phrase “Mitoxantron has low potential for bioaccumulation”."

Toxicity: No data.

Risk

"According to the European Medicines Agency guideline on environmental risk assessment of medicinal products (EMA/CHMP/SWP/4447/00), use of mitoxantron is unlikely to represent a risk for the environment, because the predicted environmental concentration (PEC) is below the action limit 0,01 μg/L."

Risk of environmental impact of mitoxantrone cannot be excluded, since no ecotoxicity data are available.

Author: Health and Medical Care Administration, Region Stockholm