Nifedipine

Summary

Persistence. Nifedipine is slowly degraded in the environment.

Bioaccumulation. The potential for bioaccumulation of nifedipine cannot be excluded, due to lack of data.

Toxicity. It cannot be excluded that nifedipine is toxic, due to lack of data.

Risk. Risk of environmental impact of nifedipine cannot be excluded, since no ecotoxicity data are available.

This summary information comes from fass.se.

Detailed information

Fass environmental information

Fass environmental information for Adalat Oros (nifedipine) from Bayer(retrieved on 2026-01-09).

Hazard

Persistence: In a photolysis study, nifedipine showed degradation at visible wavelengths, forming nitrosophenylpyridine. Based on the rate constants, half‑lives below 40 days are expected. The substance does not meet the criteria for ready biodegradability but shows significant mineralisation, supporting the phrase "Nifedipine is slowly degraded in the environment."

Bioaccumulation: No data.

Toxicity: No data.

Risk

PEC/PNEC is based on sales data in Sweden in year 2022.

PEC = 0.00242 microg/L.

Risk of environmental impact of nifedipine cannot be excluded, since no ecotoxicity data are available.

Author: Health and Medical Care Administration, Region Stockholm