Paricalcitol
Summary
Persistence. It cannot be excluded that paricalcitol is persistent, as data are lacking.
Bioaccumulation. Paricalcitol has high potential for bioaccumulation.
Toxicity. It cannot be excluded that paricalcitol is toxic, as data are lacking.
Risk. Risk of environmental impact of paricalcitol cannot be excluded, due to the lack of environmental toxicity data.
This summary information comes from fass.se.
Detailed information
Fass environmental information
Fass environmental information for Zemplar (paricalcitol), downloaded 2019-04-24.
Hazard
Persistence: No data.
Bioaccumulation: "The result was Log Dow = 5.83 at pH 7.4 (guideline e.g. OECD 107). [...] Since log Dow > 4 at pH 7.4, paricalcitol has high potential for bioaccumulation."
Toxicity: No data.
Risk
"According to the European Medicines Agency guideline on environmental risk assessment of medicinal products (EMA/CHMP/SWP/4447/00), use of paricalcitol is unlikely to represent a risk for the environment, because the predicted environmental concentration (PEC) is below the action limit of 0.01 μg/L."
References
Author: Health and Medical Care Administration, Region Stockholm
