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Hazard - P - B 3 T - Risk Cannot be excluded


Underlying data for B and risk are from Fass.

Fass environmental information

Fass environmental information for Zemplar (paricalcitol), downloaded 2019-04-24.


Persistence: No data.

Bioaccumulation: "The result was Log Dow = 5.83 at pH 7.4 (guideline e.g. OECD 107). [...] Since log Dow > 4 at pH 7.4, paricalcitol has high potential for bioaccumulation."

Toxicity: No data.


"According to the European Medicines Agency guideline on environmental risk assessment of medicinal products (EMA/CHMP/SWP/4447/00), use of paricalcitol is unlikely to represent a risk for the environment, because the predicted environmental concentration (PEC) is below the action limit of 0.01 μg/L."

Author: Health and Medical Care Administration, Region Stockholm