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Salbutamol

Information

This summary information comes from Fass.

Persistence. Salbutamol is potentially persistent.
Bioaccumulation. Salbutamol has low potential for bioaccumulation.
Toxicity. Salbutamol has low chronic toxicity. However, data are only available for one trophic level.
Risk. Risk of environmental impact cannot be excluded, since there is not sufficient ecotoxicity data available. It is voluntary for manufacturers to provide information on environmental impact on fass.se.

Detailed information

Fass environmental information

Fass environmental information for Ventoline (salbutamol) from GlaxoSmithKline (dowloaded 2021-07-06).

Hazard

Persistence: "Ready degradability: 1% degradation in 28 days (TAD 3.11). Soil Degradation: 1.3 to 38.7% degradation in 64d (TAD 3.12). [...] Salbutamol is not readily degradable or inherently degradable. The phrase “Salbutamol is potentially persistent in the environment” is thus chosen."

Bioaccumulation: Log Dow = -2.80 at pH 7.

Toxicity: There are data for 1 trophic level: crustacean (Ceriodaphnia dubia) NOEC 8 days (reproduction) 100 mg/L.

Risk

Sales data are available in Sweden for 2018. PEC/PNEC: "Risk of environmental impact of salbutamol cannot be excluded, since there is not sufficient ecotoxicity data available."

Pharmaceutial residues in the aquatic environment

Report Pharmaceutial residues in the Stockholm aquatic environment. Salbutamol has been measured in concentrations up to 15 ng/L in outgoing water from wastewater treatment plants and has also been detected in Stockholm's inner city out in the archipelago in concentrations between 01, and 0.4 ng/L.

Author: Health and Medical Care Administration, Region Stockholm