Assessment report for Ozempic (semaglutide), 14 December 2017, EMA/CHMP/715701/2017.
"The active substance is a peptide. Therefore, semaglutide is not expected to pose a risk to the environment."
Fass environmental information for Ozempic from Novo Nordisk (downloaded 2019-10-15).
The use of amino acids, proteins and peptides is not expected to have any environmental impact.
According to the European Medicines Agency guideline on environmental risk assessments for pharmaceuticals (EMA/CHMP/SWP/4447/00), vitamins, electrolytes, amino acids, peptides, proteins, carbohydrates, lipids proteins, vaccines and herbal medicinal products are exempted because they are unlikely to result in significant risk to the environment.
Even though biomolecules, such as vaccines and hormones, are exempted they should still be regarded as biologically active.
Author: Health and Medical Care Administration, Region Stockholm