According to EMA's assessment report, EMA / CHMP/853224/2016, tofacitinib is slowly degraded in the environment and has low potential for bioaccumulation. The T-value is usually based on data on acute toxicity, but since no information of acute toxicity is available, T has been calculated on the chronic toxicity, NOEC 2.9 mg/L for fish.
Environmental information for the substance is not available on fass.se. It is voluntary for manufacturers to publish environmental impact information on fass.se.
Author: Health and Medical Care Administration, Region Stockholm