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Hazard 4* P 3* B 0 T 1 Risk Insignificant

The T-value in the score for hazard refers to acute toxicity. Underlying data for P, B, T and risk are from Fass.

Fass environmental information

Fass environmental information for Topimax (Topiramate) from Janssen (downloaded 2019-12-04).


Persistence: No data.

Bioaccumulation: Log Kow = 0.5 (pH = 6.0).

Toxicity: There are data for 3 trophic levels, most sensitive algae (Pseudokirchneriella subcapitata) 93 000 microg/L.


PEC/PNEC is based on sales data in Sweden in year 2016. PEC/PNEC = 0.000411709 which gives the risk insignificant.

Author: Health and Medical Care Administration, Region Stockholm