Vardenafil
Summary
Persistence. Vardenafil is potentially persistent.
Bioaccumulation. Vardenafil has potential for bioaccumulation according to fass.se.
Toxicity. Vardenafil has very high acute toxicity.
Risk. Available ecotoxicological data do not exclude the risk of environmental impact.
This summary information comes from fass.se 2011-05-16. Environmental information is missing on fass.se for vardenafil (2025-10-06).
Detailed information
Fass environmental information
Fass environmental information Levitra (vardenafil) from Bayer (downloaded 2011-05-16).
Hazard
Persistence: "The study was performed according to Council Dir. 92/69/EEC, C.4-E (Closed bottle test).The test substance was incubated in aqueous solutions for 28 days it. Additionally, a reference substance was tested as control. Additional vessels without any test or reference substance were used as blank (control). The biological degradation of the test and reference substances was evaluated by the decrease of dissolved oxygen in the solutions. No degradation of the test substance was observed."
Bioaccumulation: Log Pow = 3.2.
Acute toxicity: Data available for 1 trophic level for crustaceans (Daphnia magna) 2 800 microg/L.
Risk
PEC = 0.0004 microg/L. Sales data Sweden year 2009.
"The risk of the potential environmental impact cannot be evaluated, however some ecotoxicity data are available."
Author: Health and Medical Care Administration, Region Stockholm