Zolpidem
Information
Hazard 5 P 3 B 0 T 2 Risk See below
Zolpidem is poorly investigated, but existing data indicate low environmental risk.
Zolpidem has been detected in treated wastewater in Stockholm County in the last five years (2012-2016).
Zolpidem is a benzodiazepine-like hypnotic. The benzodiazepine oxazepam has been shown to alter the behavior of fish which can give potential effects on the ecological balance. Further research is ongoing.
The risk classification insignificant, according to Fass.se, is based on total sold amount (kg) of the substance in Sweden during the year 2014 and the toxicity of the substance.
References
- Goodpoint. Prioritering av läkemedel med miljörisk inom SLL. Stockholm: Goodpoint; 2016. Rapport LS 2016–0634.
- SLL. Sammanställning av läkemedelsprovtagningar - Bearbetning av regional försäljningsstatistik av läkemedel samt datamaterial från Stockholms läns landstings mätprogram för läkemedelssubstanser i vattenmiljö, 2012–2016.
- IVL Swedish Environmental Research Institute Ltd. Fick J, Lindberg RH, Kaj L, Brorström-Lundén E. Results from the Swedish National Screening Programme 2010. Subreport 3, B 2014 Pharmaceuticals.
- IVL Swedish Environmental Research Institute Ltd Fick J, Lindberg RH, Fång J, Magnér J, Kaj L, Brorström-Lundén E. Screening 2014. Analysis of pharmaceuticals and hormones in samples from WWTPs and receiving waters. Rapport C 135.
- Brodin T, Fick J, Jonsson M, Klaminder J. (2013) Dilute Concentrations of a Psychiatric Drug Alter Behavior of Fish from Natural Populations. Science 339(6121): 814-815.
- Fick J, Lindberg RH, Tysklind M, Larsson DG. Predicted critical environmental concentrations for 500 pharmaceuticals. Regul Toxicol Pharmacol. 2010;58:516-23.
- Fass.se för vårdpersonal
Author: Health and Medical Care Administration, Region Stockholm