Ofloxacin is a racemate. One of the enantiomers is levofloxacin (S-enantiomer). Therefore, see also environmental information for levofloxacin. In analyzes of ofloxacin in water both ofloxacin and levofloxacin are measured.
Previously, there was some risk for the selection of antibiotic resistant bacteria in wastewater treatment plants, but sales in Stockholm County have fallen sharply in recent years, and so the levels in wastewater have also decreased. At present only eye drops with ofloxacin have marketing authorisation.
Studies have shown that even low concentrations of antibiotics in the environment may trigger antibiotic resistance and should therefore be taken to ensure that as little as possible end up in our environment.
Author: The Pharmaceutical unit of Region Stockholm