Parikalcitol

Sammanfattning

Fara - P - B 3 T - Risk Kan inte uteslutas

Underliggande data om B och risk kommer från Fass.

Fass miljöinformation

Fass miljöinformation för Zemplar (parikalcitol), hämtad 2019-04-24.

Fara

Persistens: Inga data.

Bioackumulation: "The result was Log D_ow = 5.83 at pH 7.4 (guideline e.g. OECD 107). [...] Since log D_ow > 4 at pH 7.4, paricalcitol has high potential for bioaccumulation."

Toxicitet: Inga data.

Risk

"According to the European Medicines Agency guideline on environmental risk assessment of medicinal products (EMA/CHMP/SWP/4447/00), use of paricalcitol is unlikely to represent a risk for the environment, because the predicted environmental concentration (PEC) is below the action limit of 0.01 μg/L."